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Source – Druginfozone – A study published in Annals of Allergy, Asthma and Immunology 2006; 96(5): 731-735 suggests that
adding oral montelukast to inhaled beta-agonist therapy may be beneficial in acute asthma in pre-school childrenaged (2-5 years)
A randomised, double-blind, placebo-controlled parallel-group study of 51 patients (2-5 years old) experiencing mild to moderate asthma
received 4mg of montelukast or placebo in addition to inhaled salbutamol and were followed up for 4 hours. The researchers’ monitored the pulmonary index score, respiratory rate, and pulse.
The researchers concluded that a 4mg dose of montelukast had the potential to provide additive clinical benefit in mild to moderate
acute asthma in pre-school children.
4mg montelukast chewable tablets are licensed for children aged 2 -5 years.
For more information go to: http://www.druginfozone.nhs.uk/record%20viewing/viewRecord.aspx?id=5670 59
Prepared by Susan Wileman Medicines Information Technician
Date of Preparation: 26th June 2006
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