Title:

Antibiotic Use in Babies Increases Risk of Asthma in Childhood?

Date:

14th March 2006

Author:

Susan Wileman Medicines Information Technician

 

Source - NEW YORK (Reuters Health) – A report in Chest 2006; 129:610-618 suggests that exposure to antibiotics in the first year of life may increase the risk of developing asthma later in childhood. In fact, there may even be a higher risk with each additional course of antibiotics.

The researchers noted that the prevalence of asthma in western countries has increased over the last three decades. In the same period there has been a greater exposure of infants to antibiotics, but epidemiologic evidence linking antibiotic use with asthma risk is conflicting.

To review the available evidence, the researchers identified seven studies which included 12,082 children and 1817 asthma cases that specifically examined the relationship between being given at least one prescription for an antibiotic in the first year of life and the development of physician-diagnosed asthma between the ages of 1 and 18 years.

Overall, the pooled data showed that the likelihood of developing asthma was doubled among children with antibiotic exposure before 1 year of age.

For more information go to: http://www.reutershealth.com/archive/2006/03/13/eline/links/20060313elin036 .html

Prepared by Susan Wileman Medicines Information Technician

Date of Preparation: 14th March 2006