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Source – Pharmaceutical Journal (5/11/05) - A new antibiotic drug delivery system designed to improve compliance and dosing accuracy when administering drugs to children has been launched by Grünenthal.The system, called Clarosip, is a drinking straw that contains neutral tasting granules of clarithromycin. When a child sips a cold or warm drink through the straw a dose of the antibiotic is delivered. A filter/controller on the straw shows when the complete dose has been taken.
The straw is available in three doses — 125mg, 187.5mg and 250mg — given twice daily. It is indicated for the treatment of upper
respiratory tract infections, acute otitis media, lower respiratory tract infections, sinusitis and acute exacerbations of chronic bronchitis, and skin and soft tissue infections.
A clinical trial involving 266 children compared Clarosip with clarithromycin administered via a graduated syringe. Full treatment
adherence was higher in the Clarosip group than the syringe group (93.7 per cent versus 85.9 per cent, P=0.0370). In addition, ease of use and dosing accuracy was considered simple or very simple
by more parents in the Clarosip group.
For more information go to: http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid= 17014
Prepared by Susan Wileman Medicines Information Technician
Date of Preparation: 8th November 2005
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