Title:

Positive Clinical Trial Results for Keppra® as Adjunctive Therapy in the Treatment of Primary Generalised Tonic-Clonic Seizures

Date:

1st November 2005

Author:

Susan Wileman Medicines Information Technician

 

Source – Medi-lexicon - UCB announced positive clinical trial results from a study evaluating Keppra® (levetiracetam) as adjunctive treatment in adult and paediatric patients (4-65 years of age) suffering from idiopathic generalised epilepsy (IGE), with primary generalised tonic-clonic (PGTC) seizures. The results of this phase III, double-blind, multicentre, randomised, placebo-controlled study in 164 patients demonstrated that Keppra® significantly reduced the frequency of PGTC seizures when compared with placebo. Seizures were previously uncontrolled despite treatment with one or two concomitant anti-epileptic drugs.

Keppra® is currently indicated in the UK as adjunctive therapy in the treatment of partial onset seizures with or without secondary generalisation in adults and children from 4 years of age with epilepsy.

For more information go to:

http://www.pharma-lexicon.com/medicalnews.php?newsid=32831

Prepared by Susan Wileman Medicines Information Technician

Date of Preparation: 1st November 2005